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Raid failure banner.png
Mammoth Cyst
Mammoth Cyst.png
Enemy Class Eldritch/Beast
Size Gigantic (3)
Actions per round Turnticker.pngTurnticker.png
HP 158
HP (Stygian/Bloodmoon) 190
Dodge 23.75%
Protection 25%
Speed 3
Tray stealth.png Stealth No
Poptext stun.png Stun 97.5%
Poptext poison.png Blight 87.5%
Poptext bleed.png Bleed 67.5%
Poptext debuff.png Debuff 67.5%
Poptext move.png Move 73%

Mammoth Cyst is a miniboss-type enemy found on the third quest in the Darkest Dungeon. There are multiple copies of it, but only the one that guards the quest curio must be killed to complete the quest.


The Cyst has two actions per turn and will alternate between its 2 main attacks, which can attack either one or two Heroes in any rank. When brought down to half health it will start to heal itself from time to time. It will resummon the White Cell Stalk each time it's killed. Bring Antivenom and Medicinal Herbs to counteract negative effects of its attacks. The main problem of the fight is the White Cell Stalk's Teleport, which can be rarely dodged, so do not rely on dodging it, and on a hit sends your party to a random dead end on the map. It is recommended to use stuns to prevent that, or simply trying to find a way around these fights to the center, where the quest objective is. The health bar of the Cyst will not reset after the Teleport.

Team Selection[]

Preferred Heroes[]

  • Plague Doctor - Her Blinding Gas can stun both the Cyst and White Cell Stalk at the same time, and Plague Grenade can Blight them simultaneously.
  • Houndmaster - PROT-reducing Whistle combined with his bonus damage against Beasts makes him a strong damage dealer in the fight.
  • Hellion - Iron Swan can reliably snipe and kill the White Cell Stalk before a Teleport happens.
  • Flagellant - Rain of Sorrows will hit both targets and apply a hefty Bleed. He can also heal and relieve Stress in a pinch.
  • Shieldbreaker - Capable of reaching the White Cell Stalk or even pulling it to the front. Also pierces the Mammoth Cyst's PROT.

Reasonable Choices[]

  • Arbalest/Musketeer - Long-range damage lets her snipe the White Cell Stalk, and her main attack is great with a Mark party.
  • Occultist - Bonus damage against Eldritch enemies. Abyssal Artillery can hit both targets at once. Single-target healing may have difficulties keeping the party together in the long run.
  • Bounty Hunter - His Mark for Death also reduces PROT, and his Planned Takedown Camp buff raises his damage on the Cyst. Has difficulty reaching the White Cell Stalk.
  • Grave Robber - Work in tandem with a Plague Doctor to deliver high damage to a Blighted White Cell Stalk, or use Pick to the Face to smash through the Mammoth Cyst's PROT.

Discouraged Heroes[]

  • Leper - Can't reliably hit the White Cell Stalk on his own, and will require PROT reduction to make good dents against the Cyst.
  • Crusader - Struggles a little on hitting and damaging both targets.
  • Antiquarian - Dragging out a fight with her defensive skill set means a higher chance of being Teleported.


Darkest Level
Skill Name Range Rank Target Accuracy Crit
Damage Effect
Bulging Gaze Ranged 1, 2, 3, 4. 1, 2, 3, 4, 25% +1 Target. 113.75% 0% 8-13 Tray afflicted.png 80% Stress +15
Poptext debuff.png 150% Debuff: -20% DMG
No Effect
Digestion Ranged 1, 2, 3, 4. 1, 2, 3, 4, 25% +1 Target. 113.75% 3% 8-17 Poptext poison.png 150% Blight 8 No Effect
Revivify Support 1, 2, 3, 4. Self No Effect Skill attribute heal.png Heal 10-20
Poptext buff.png Buff: +25% DMG
Summon Support 1, 2, 3, 4. 1, 2, 3, 4 (allies). New game plus save icon.png Summon White Cell Stalk No Effect

Related Enemies[]

The Darkest Dungeon[]



Regional Necromancer MiniScrollpip.png Prophet MiniScrollpip.png Hag MiniScrollpip.png Brigand Pounder MiniScrollpip.png Swine Prince MiniScrollpip.png Flesh MiniScrollpip.png Siren MiniScrollpip.png Drowned Crew
Roaming / Event Shambler MiniScrollpip.png Collector MiniScrollpip.png FanaticThe Crimson Court DLC MiniScrollpip.png Thing from the StarsExclusive to The Color of Madness DLC MiniScrollpip.png Shrieker MiniScrollpip.png Brigand Vvulf
Boss Minions Cauldron MiniScrollpip.png Brigand Matchman MiniScrollpip.png Shambler MiniScrollpip.png Wilbur MiniScrollpip.png Drowned Anchorman MiniScrollpip.png Shrieker's Nest MiniScrollpip.png Barrel O' Bombs
CourtyardThe Crimson Court DLC Baron MiniScrollpip.png Viscount MiniScrollpip.png Countess MiniScrollpip.png Crocodilian MiniScrollpip.png Garden Guardian
FarmsteadExclusive to The Color of Madness DLC Miller MiniScrollpip.png Fracture MiniScrollpip.png Sleeper
Darkest DungeonContains spoilers for the Darkest Dungeon
Shuffling Horror MiniScrollpip.png Templar Impaler MiniScrollpip.png Templar Warlord MiniScrollpip.png Mammoth Cyst MiniScrollpip.png Ancestor MiniScrollpip.png Heart of Darkness